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1

Effects of Ethanol on Excitatory and Inhibitory Synaptic Transmission in Rat Cortical Neurons

Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z. Yeh, Toshio Narahashi

Journal:

Alcoholism: Clinical and Experimental Research

Year:

2007

Language:

english

File:

PDF, 563 KB

english, 2007

2

Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N -methyl- D -aspartate receptor

Moriguchi, Shigeki, Tanaka, Tomoya, Narahashi, Toshio, Fukunaga, Kohji

Journal:

Year:

2013

Language:

english

File:

PDF, 1.69 MB

english, 2013

3

Stimulation of Sigma-1 Receptor Ameliorates Depressive-like Behaviors in CaMKIV Null Mice

Moriguchi, Shigeki, Sakagami, Hiroyuki, Yabuki, Yasushi, Sasaki, Yuzuru, Izumi, Hisanao, Zhang, Chen, Han, Feng, Fukunaga, Kohji

Journal:

Molecular Neurobiology

Year:

2015

Language:

english

File:

PDF, 4.62 MB

english, 2015

4

Donepezil-induced Neuroprotection of Acetylcholinergic Neurons in Olfactory Bulbectomized Mice

YAMAMOTO, Yui, SHIODA, Norifumi, HAN, Feng, MORIGUCHI, Shigeki, FUKUNAGA, Kohji

Journal:

YAKUGAKU ZASSHI

Year:

2010

File:

PDF, 385 KB

2010

5

Memantine improves cognitive function via KATP channel inhibition

Moriguchi, Shigeki, Fukunaga, Kohji

Journal:

Folia Pharmacologica Japonica

Year:

2017

File:

PDF, 849 KB

2017

6

ChemInform Abstract: Donepezil-Induced Neuroprotection of Acetylcholinergic Neurons in Olfactory Bulbectomized Mice

Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Kohji Fukunaga

Journal:

Year:

2010

File:

PDF, 15 KB

2010

7

ChemInform Abstract: Neurochemical Mechanisms of a Novel Alzheimer′s Disease Therapeutics on Improvement of Cognition and Depressive Behavior

Norifumi Shioda, Yui Yamamoto, Feng Han, Shigeki Moriguchi, Kohji Fukunaga

Journal:

Year:

2011

File:

PDF, 18 KB

2011

8

Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation

Shigeki Moriguchi, Norifumi Shioda, Feng Han, Jay Z. Yeh, Toshio Narahashi, Kohji Fukunaga

Journal:

Year:

2009

Language:

english

File:

PDF, 652 KB

english, 2009

9

Reduced expression of the ATRX gene, a chromatin-remodeling factor, causes hippocampal dysfunction in mice

Tatsuya Nogami, Hideyuki Beppu, Takashi Tokoro, Shigeki Moriguchi, Norifumi Shioda, Kohji Fukunaga, Toshihisa Ohtsuka, Yoko Ishii, Masakiyo Sasahara, Yutaka Shimada, Hisao Nishijo, En Li, Isao Kitajim

Journal:

Year:

2011

Language:

english

File:

PDF, 563 KB

english, 2011

10

Aberrant hippocampal spine morphology and impaired memory formation in neuronal platelet-derived growth factor beta-receptor lacking mice

Norifumi Shioda, Shigeki Moriguchi, Takeshi Oya, Yoko Ishii, Jie Shen, Takako Matsushima, Hisao Nishijo, Masakiyo Sasahara, Kohji Fukunaga

Journal:

Year:

2012

Language:

english

File:

PDF, 2.14 MB

english, 2012

11

Enhancement ofN-methyl-D-aspartate receptor-mediated excitatory postsynaptic potentials in the neostriatum after methamphetamine sensitization

Shigeki Moriguchi, Shigenori Watanabe, Hitoshi Kita, Hiroshi Nakanishi

Journal:

Experimental Brain Research

Year:

2002

Language:

english

File:

PDF, 108 KB

english, 2002

12

Functional Crosstalk Between Cell-Surface and Intracellular Channels Mediated by Junctophilins Essential for Neuronal Functions

Sho Kakizawa, Shigeki Moriguchi, Atsushi Ikeda, Masamitsu Iino, Hiroshi Takeshima

Journal:

Year:

2008

Language:

english

File:

PDF, 271 KB

english, 2008

13

Decreased calcium/calmodulin-dependent protein kinase II and protein kinase C activities mediate impairment of hippocampal long-term potentiation in the olfactory bulbectomized mice

Shigeki Moriguchi, Feng Han, Osamu Nakagawasai, Takeshi Tadano, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 284 KB

english, 2006

14

Generation of constitutively active calcineurin by calpain contributes to delayed neuronal death following mouse brain ischemia

Norifumi Shioda, Shigeki Moriguchi, Yasufumi Shirasaki, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 375 KB

english, 2006

15

Constitutively active calcineurin mediates delayed neuronal death through Fas-ligand expression via activation of NFAT and FKHR transcriptional activities in mouse brain ischemia

Norifumi Shioda, Feng Han, Shigeki Moriguchi, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2007

Language:

english

File:

PDF, 1.25 MB

english, 2007

16

CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region

Shigeki Moriguchi, Norifumi Shioda, Feng Han, Toshio Narahashi, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2008

Language:

english

File:

PDF, 653 KB

english, 2008

17

Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice

Shigeki Moriguchi, Feng Han, Norifumi Shioda, Yui Yamamoto, Takeharu Nakajima, Osamu Nakagawasai, Takeshi Tadano, Jay Z. Yeh, Toshio Narahashi, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2009

Language:

english

File:

PDF, 670 KB

english, 2009

18

Sigma-1 receptor stimulation by dehydroepiandrosterone ameliorates cognitive impairment through activation of CaM kinase II, protein kinase C and extracellular signal-regulated kinase in olfactory bulbectomized mice

Shigeki Moriguchi, Yui Yamamoto, Tatsuya Ikuno, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2011

Language:

english

File:

PDF, 529 KB

english, 2011

19

Reduced calcium/calmodulin-dependent protein kinase II activity in the hippocampus is associated with impaired cognitive function in MPTP-treated mice

Shigeki Moriguchi, Yasushi Yabuki, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 410 KB

english, 2012

20

The T-type voltage-gated calcium channel as a molecular target of the novel cognitive enhancer ST101: enhancement of long-term potentiation and CaMKII autophosphorylation in rat cortical slices

Shigeki Moriguchi, Norifumi Shioda, Yui Yamamoto, Hideaki Tagashira, Kohji Fukunaga

Journal:

Journal of Neurochemistry

Year:

2012

Language:

english

File:

PDF, 451 KB

english, 2012

21

DY-9760e, a Novel Calmodulin Inhibitor, Exhibits Cardioprotective Effects in the Ischemic Heart

Kohji Fukunaga, Feng Han, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Yasufumi Shirasaki

Journal:

Cardiovascular Therapeutics

Year:

2006

Language:

english

File:

PDF, 161 KB

english, 2006

22

Cardioprotective Effect of Vanadyl Sulfate on Ischemia/Reperfusion-Induced Injury in Rat Heart In vivo Is Mediated by Activation of Protein Kinase B and Induction of FLICE-Inhibitory Protein

Md. Shenuarin Bhuiyan, Yoko Takada, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Kohji Fukunaga

Journal:

Cardiovascular Therapeutics

Year:

2008

Language:

english

File:

PDF, 6.28 MB

english, 2008

23

Imbalance between CaM kinase II and calcineurin activities impairs caffeine-induced calcium release in hypertrophic cardiomyocytes

Ying-Mei Lu, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Jiro Kasahara, Yasufumi Shirasaki, Zheng-Hong Qin, Kohji Fukunaga

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.09 MB

english, 2007

24

Lithium-induced activation of Akt and CaM kinase II contributes to its neuroprotective action in a rat microsphere embolism model

Takuya Sasaki, Feng Han, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Koichi Ishiguro, Kohji Fukunaga

Journal:

Year:

2006

Language:

english

File:

PDF, 475 KB

english, 2006

25

Nobiletin improves brain ischemia-induced learning and memory deficits through stimulation of CaMKII and CREB phosphorylation

Yui Yamamoto, Norifumi Shioda, Feng Han, Shigeki Moriguchi, Akira Nakajima, Akihito Yokosuka, Yoshihiro Mimaki, Yutaka Sashida, Tohru Yamakuni, Yasushi Ohizumi, Kohji Fukunaga

Journal:

Year:

2009

Language:

english

File:

PDF, 725 KB

english, 2009

26

Heparin-binding EGF-like growth factor is required for synaptic plasticity and memory formation

Atsushi Oyagi, Shigeki Moriguchi, Atsumi Nitta, Kenta Murata, Yasuhisa Oida, Kazuhiro Tsuruma, Masamitsu Shimazawa, Kohji Fukunaga, Hideaki Hara

Journal:

Year:

2011

Language:

english

File:

PDF, 714 KB

english, 2011

27

Cytoprotective effect of bis(1-oxy-2-pyridinethiolato)oxovanadiun(IV) on myocardial ischemia/reperfusion injury elicits inhibition of Fas ligand and Bim expression and elevation of FLIP expression

Md. Shenuarin Bhuiyan, Masatoshi Shibuya, Norifumi Shioda, Shigeki Moriguchi, Jiro Kasahara, Yosiharu Iwabuchi, Kohji Fukunaga

Journal:

European Journal of Pharmacology

Year:

2007

Language:

english

File:

PDF, 721 KB

english, 2007

28

Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus

Kentaro Matsuzaki, Kenichi Miyazaki, Seiichiro Sakai, Hiromu Yawo, Norihito Nakata, Shigeki Moriguchi, Kohji Fukunaga, Akihito Yokosuka, Yutaka Sashida, Yoshihiro Mimaki, Tohru Yamakuni, Yasushi Ohizu

Journal:

European Journal of Pharmacology

Year:

2008

Language:

english

File:

PDF, 425 KB

english, 2008

29

The induction of reactive oxygen species and loss of mitochondrial Omi/HtrA2 is associated with S-nitrosoglutathione-induced apoptosis in human endothelial cells

Qi-bing Liu, Lu-lu Liu, Ying-mei Lu, Rong-rong Tao, Ji-yun Huang, Norifumi Shioda, Shigeki Moriguchi, Kohji Fukunaga, Feng Han, Yi-jia Lou

Journal:

Toxicology and Applied Pharmacology

Year:

2010

Language:

english

File:

PDF, 1.88 MB

english, 2010

30

Involvement of enhanced sensitivity of N-methyl-d-aspartate receptors in vulnerability of developing cortical neurons to methylmercury neurotoxicity

Ken-ichiro Miyamoto, Hiroshi Nakanishi, Shigeki Moriguchi, Naoto Fukuyama, Komyo Eto, Junji Wakamiya, Koji Murao, Kimiyoshi Arimura, Mitsuhiro Osame

Journal:

Year:

2001

Language:

english

File:

PDF, 979 KB

english, 2001

31

Anesthetics modulate the release of glutamate and GABA via neuronal nicotinic acetylcholine receptors

Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh, Toshio Narahashi

Journal:

International Congress Series

Year:

2005

Language:

english

File:

PDF, 191 KB

english, 2005

32

Unique mechanism of action of Alzheimer's drugs on brain nicotinic acetylcholine receptors and NMDA receptors

Toshio Narahashi, William Marszalec, Shigeki Moriguchi, Jay Z Yeh, Xilong Zhao

Journal:

Year:

2003

Language:

english

File:

PDF, 206 KB

english, 2003

33

Ca2+/calmodulin-dependent protein kinase II and protein kinase C activities mediate extracellular glucose-regulated hippocampal synaptic efficacy

Shigeki Moriguchi, Yutaka Oomura, Norifumi Shioda, Feng Han, Nobuaki Hori, Shuji Aou, Kohji Fukunaga

Journal:

Molecular and Cellular Neuroscience

Year:

2011

Language:

english

File:

PDF, 938 KB

english, 2011

34

Potentiation of NMDA receptor-mediated synaptic responses by microglia

Shigeki Moriguchi, Yoshito Mizoguchi, Yoshiro Tomimatsu, Yoshinori Hayashi, Tomoko Kadowaki, Yoshifumi Kagamiishi, Nobuo Katsube, Kenji Yamamoto, Kazuhide Inoue, Shigenori Watanabe, Junichi Nabekura,

Journal:

Molecular Brain Research

Year:

2003

Language:

english

File:

PDF, 395 KB

english, 2003

35

Downregulation of glutamate transporters is associated with elevation in extracellular glutamate concentration following rat microsphere embolism

Feng Han, Norifumi Shioda, Shigeki Moriguchi, Zheng-Hong Qin, Kohji Fukunaga

Journal:

Neuroscience Letters

Year:

2008

Language:

english

File:

PDF, 999 KB

english, 2008

36

Nefiracetam potentiates NMDA receptor function via protein kinase C activation

Shigeki Moriguchi, Norifumi Shioda, Toshio Narahashi, Kohji Fukunaga

Journal:

Neuroscience Research

Year:

2007

Language:

english

File:

PDF, 81 KB

english, 2007

37

Changes in hippocampal spine morphology and synaptic plasticity induced by conditional loss of PDGFR-β are associated with memory impairment in mutant mice

Norifumi Shioda, Shigeki Moriguchi, Yui Yamamoto, Takako Matsushima, Masakiyo Sasahara, Kohji Fukunaga

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 87 KB

english, 2009

38

Important role of diacylglycerol kinase β in spine formation and memory

Yasuhito Shirai, Takeshi kozuki, Kenichi Kakefuda, Atsushi Ohyagi, Kyouji Horie, Shigeki Moriguchi, Masamitsu Simazawa, Kohji Fukunaga, Jyunnji Takeda, Naoaki Saito, Hideaki Hara

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 70 KB

english, 2009

39

CaM kinase II activation is essential for cognitive function through Na+/Ca2+ exchanger type 2

Shigeki Moriguchi, Feng Han, Norifumi Shioda, Satomi Kita, Issei Komuro, Takahiro Iwamoto, Kohji Fukunaga

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 74 KB

english, 2009

40

Sigma-1 receptor stimulation by dehydroepiandeosterone (DHEA) ameliorates the cognitive deficits via CaMKII, PKC and ERK activities in olfactory bulbectomized mice

Shigeki Moriguchi, Yui Yamamoto, Kohji Fukunaga

Journal:

Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 106 KB

english, 2011

41

Proteases involved in long-term potentiation

Yoshiro Tomimatsu, Satoru Idemoto, Shigeki Moriguchi, Shigenori Watanabe, Hiroshi Nakanishi

Journal:

Year:

2002

Language:

english

File:

PDF, 186 KB

english, 2002

42

Central administration of a nitric oxide synthase inhibitor causes pressor responses via the sympathetic nervous system and the renin-angiotensin system in Wistar rats

Shigeki Moriguchi, Noriyasu Ohzuru, Nobuhiro Koga, Kenji Honda, Ryo Saito, Yukio Takano, Hiro-o Kamiya

Journal:

Neuroscience Letters

Year:

1998

Language:

english

File:

PDF, 120 KB

english, 1998

43

T-type voltage-gated calcium channel activated by ST101 is a novel molecular target as cognitive enhancer

Shigeki Moriguchi, Kohji Fukunaga

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 51 KB

english, 2012

44

508 Studies on the centrally administered nitric oxide synthesis inhibitor on the cardiovascular regulation system

Shigeki Moriguchi, Noriyasu Ohzuru, Kenji Honda, Ryo Saito, Yukio Takano, Hiro-o Kamiya

Journal:

Neuroscience Research

Year:

1997

Language:

english

File:

PDF, 111 KB

english, 1997

45

Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice

Moriguchi, Shigeki, Tanaka, Tomoya, Tagashira, Hideaki, Narahashi, Toshio, Fukunaga, Kohji

Journal:

Behavioural Brain Research

Year:

2013

Language:

english

File:

PDF, 876 KB

english, 2013

46

P4-240: Potentiation of calcium/calmodulin–dependent protein kinase I I benefits for cognitive enhancement in Alzheimer's disease patients

Moriguchi, Shigeki, Han, Feng, Shioda, Norifumi, Narahashi, Toshio, Fukunaga, Kohji

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 63 KB

english, 2008

47

Novel Alzheimer's therapeutics: ST101 enhances acetylcholine release through T-type voltage-gated calcium channel

Fukunaga, Kohji, Yamamoto, Yui, Moriguchi, Shigeki, Shioda, Norifumi

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 47 KB

english, 2012

48

Abnormal behavior of methamphetamine-induced sensitization is associated with impaired CaM kinase II activity in junctophilin deficient mice

Moriguchi, Shigeki, Takeshima, Hiroshi, Fukunaga, Kohji

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 68 KB

english, 2010

49

AN OCCUPATION NEUROSIS OF THE LOWER LIMB.

Moriguchi, Shigeki, Takeshima, Hiroshi, Fukunaga, Kohji

Journal:

Year:

1917

Language:

english

File:

PDF, 193 KB

english, 1917

50

Memantine ameliorates the impairment of hippocampal long-term potentiation in olfactory bulbectomized mice.

Moriguchi, Shigeki, Yamamoto, Yui, Shioda, Norifumi, Fukunaga, Kohji

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 44 KB

english, 2010